Vegetarian
Gluten-Free
No Generic Equivalent
Packaged in BPA-free bottles
Subject to more than 80 quality checks
Avmacol® Extra Strength
75 Count
Sale price
$55.99
Regular price
$65.99
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Avmacol® Extra Strength
Sale price
$55.99
Regular price
$65.99
- Contains broccoli extracts glucoraphanin and myrosinase. Our trademarked Myrosimax® enzyme ensures the presence of active myrosinase enzyme to support sulforaphane production.
- Sulforaphane promotes your body’s natural detoxification process for certain environmental threats found in the air you breathe, the food you eat, and the water you drink.*
- Research has shown sulforaphane also supports the body’s defenses against oxidative stress and cell damage.*
- The Avmacol® Brand has been selected for more human clinical trials than any other sulforaphane-producing supplement1.
- Gluten-free
- Tablets may be swallowed whole or crushed for easier consumption.
Validated with human research
Our exclusive Sulforaphane Production System® is validated in humans by measuring metabolites of sulforaphane collected in the urine.
The choice for clinical studies
Because of the Sulforaphane Production System® exclusive to Avmacol®, numerous researchers have chosen this product for clinical studies worldwide.
Promotes natural detoxification
Sulforaphane promotes your body’s natural detoxification process for certain environmental threats.
What is Avmacol® Extra Strength?
Avmacol® Extra Strength is a patented, sulforaphane-producing supplement that works in combination with Maitake mushroom extract (containing beta-glucans) to support your body's natural detoxification process better than sulforaphane alone.1Avmacol® Extra Strength provides glucoraphanin, also known as sulforaphane glucosinolate, and active myrosinase enzyme, which are the essential ingredients needed for sulforaphane production. Without active myrosinase enzyme, one may not be able to reap sulforaphane’s many health-promoting benefits.
Directions for Use
Take one (1) tablet per day with a meal. If you have a condition that requires medical attention always consult your physician before taking any dietary supplement.
OTHER INGREDIENTS:MICROCRYSTALLINE CELLULOSE, MALTODEXTRIN
1In a laboratory study, treatment of RAW 264.7 cells with the combination of Maitake mushroom extract and sulforaphane resulted in greater induction of the expression of Phase 2 enzyme NQO1 than either individual component alone.
What are the Ingredients?
Avmacol® Extra Strength contains the essential ingredients necessary for sulforaphane production in the body, broccoli seed extract (Glucoraphanin) and Myrosimax® (Active Myrosinase Enzyme). Avmacol® Extra Strength also contains Maitake mushroom extract for added immune and detoxification support.
Supplement Facts
Directions for Use:Take one (1) tablet per day. If you have a condition that requires medical attention always consult your physician before taking any dietary supplement.
OTHER INGREDIENTS: MICROCRYSTALLINE CELLULOSE, MALTODEXTRIN
CONTAINS < 2% OF: MODIFIED CELLULOSE GUM, SILICON DIOXIDE AND MAGNESIUM STEARATE
How Maitake Mushroom Extract Works in Combination with Sulforaphane
The Maitake mushroom extract (containing beta-glucans) works in combination with sulforaphane to support your body’s natural detoxification process better than sulforaphane alone.1In addition, the Maitake mushroom extract found in Avmacol® Extra Strength provides the added bonus of immune support by promoting neutrophil function and natural killer cell activity.
The Science Behind Avmacol®
Extra Strength
The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Below are images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.
Translocation of NRF2 into the Nucleus Following Exposure to Sulforaphane and Maitake Mushroom Extract
In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm (arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can bind to DNA to turn on expression of certain Phase 2 enzymes.
Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1
NQO1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.
HO-1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.
Who Would Benefit from Avmacol® Extra Strength?
We are capable of incredible things; and when our bodies get the support they need, the results can be amazing. Avmacol® unleashes the power of broccoli to help your body fight off toxin-related stress at the cellular level
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From Broccoli to Biochemistry: How Sulforaphane Supports Your Body
Sulforaphane is a result of two specific compounds:
Glucoraphanin, found in broccoli seed and sprout extract
Myrosinase, a natural enzyme that activates glucoraphanin
What is Glucoraphanin?
Glucoraphanin, also known as sulforaphane glucosinolate, is a compound that is present in many cruciferous vegetables, most notably in broccoli. It is an essential ingredient needed for sulforaphane production because it is sulforaphane’s direct precursor. The glucoraphanin is converted into sulforaphane after it is processed by an active myrosinase enzyme.
What is Myrosinase?
Myrosinase is an important enzyme required to convert glucoraphanin into sulforaphane. Additionally, it can be found in cruciferous vegetables, though it can become inactivated during the cooking process.
The Importance of Active Myrosinase Enzyme
The conversion of glucoraphanin to sulforaphane can be expressed in this simple equation:
Active myrosinase enzyme is essential for the conversion of glucoraphan into sulforaphane. Without this enzyme, it may not be possible to reap sulforaphane's many health-promoting benefits, which is why you’ll always find Myrosimax® (Active myrosinase Enzyme) in the Avmacol® brand family.Even though it is true that both glucoraphanin and the myrosinase enzyme can be found in cruciferous vegetables such as broccoli, Brussels sprouts, and cauliflower, there may not be enough of either compound to allow for adequate sulforaphane production. This can be due to seed quality, soil composition, and many other factors. Additionally, the myrosinase enzyme can be destroyed during the cooking process. So while both glucoraphanin and the myrosinase enzyme can be found in the vegetables you eat, the ones you buy from the market are not reliable sources of either compound.The Avmacol® brand contains both glucoraphanin and Myrosimax® (Active Myrosinase Enzyme), the essential ingredients needed to promote sulforaphane production.*
Customer reviews
I have been using this product for the past couple years - great way to get the benefits of broccoli sprouts without the hassle of germinating yourself. Recently I switched to Amazon vs. ordering direct to take advantage of subscribe and save.
D. Sawyer
The quality and taste seem to be okay and easy to swallow. No noticeable smell and the value for the money is good. Quality ingredients. I genuinely seem to feel better and no its not just a placebo. Like anything with supplements, you will notice more of a significant difference with time.
benny
sulforaphane is amazing, this product reduced my inflammation and cardiovascular discomfort the day i started using it :) would love to just grow and eat frozen broccoli sprouts but i don't have the time or patience for that right now.... live a healthy lifestyle and drink lots of water!
Root Khan
So I started taking these because I saw a pic of this totes ripped cow, they make my poops smell like sulphur. I switched to broccomax which did not produce the sulphur poops.i think this is an indicator of broccomax sucking at what it's supposed to be doing. I have switched back to avmacol.
Justin
Incredible. Heard about this from Dr Ronda Patrick. I’m 33 and started taking this a week ago (morning dosage), and immediately I noticed more alertness and mental clarity. Now I don’t even get tired in the afternoons. My anxiety also has gotten much better (I also take ashwagandha and resevetrol).
Lukich Family
I would highly recommend this supplement. If I could take only one supplement, and I take quite a few, this is the one I would recommend. It enhances endurance while running and seems to give me energy.
N. Music